Welcome to the newly revamped Key Developments, now twice weekly and with non-COVID news. Right now, it’s actually still just COVID news, but we’ll be slowly morphing it into something broader as we go.
There are over 20.4 million global cases. Cases have grown globally by 1.7 million since last week, which is up from the week before. Global case growth is accelerating. There have been over 742,000 deaths around the globe. There are over 5.2 million cases in the US. There have been over 167,000 deaths in the US, with about 1,000 deaths per day. The US, Brazil, and India continue to lead global case growth. Mexico is third in the world in number of deaths, at over 50,000:
Mexico has the 3rd-highest coronavirus death toll in the world, more than 52,000. And its struggle has been made even harder by a pervasive phenomenon: a deeply rooted fear of hospitals is leading many Mexicans to delay treatment until it is too latehttps://t.co/yv97xyIrG1
— Alfons López Tena 🦇 (@alfonslopeztena) August 10, 2020
The Remdesivir shortage should ease this fall. Gilead is ramping up production by millions of doses both before and after October. Pfizer will help manufacture and supply it.
There are case reports of critically ill COVID-19 patients making some recovery with a novel antiviral. Per discussion with contributor Ari Allyn-Feuer, aviptadil is a synthetic analogue of a natural peptide hormone with G-protein-coupled receptors as a target. It acts as a vasodilator, but it’s mechanism of action against COVID-19 is not clear. Clinical trials are warranted.
Most infected people don’t know their point of infection. But when you read the article, you also start to realize that people rationalize and intellectualize their symptoms. They don’t believe they’re sick when they are, they think they’re better when they’re still symptomatic, and they hang out with people thinking six feet is enough distance to be protective. Droplets can carry 27 feet…
Stop it with the hydroxycholorquine already.
One in three Americans will miss their August rent payment. The eviction moratorium is over, so evictions will be starting en masse shortly. Tens of millions of Americans are about be homeless, and it’s unclear how helpful the president’s stimulus by executive order (EO) will actually be. His EO and memoranda did not include a second stimulus check.
Here’s a lecture from experts on the current status of vaccine trials. This is really excellent work and it’s from world-class scientists and leaders in their field. Worth a watch.
The US looks to be turning a corner, but India is not looking so hot:
While the United States has made a U-turn, India is on a very worrisome trajectory pic.twitter.com/vBv9fSR8PZ
— Eric Topol (@EricTopol) August 8, 2020
Europe is on the rise, driven by cases in Spain:
A new look. United States heading down. Europe up. pic.twitter.com/QGzxgm40k4
— Eric Topol (@EricTopol) August 9, 2020
Small family gatherings are driving case growth in the US.
Masks, best to worst (and the gaiter-type is worse than none!):
New study describes a low-cost technique to measure mask effectiveness.
Take-away: from best to worst at reducing droplet transmission through mask
N95 > surgical mask > cotton mask > knitted mask > bandana > no mask > gaiter type neck fleecehttps://t.co/I47UT1b2Ll pic.twitter.com/GhfSDAvgOb
— Liz Goldberg MD ScM (@LizGoldbergMD) August 9, 2020
Use an electric cooker to sanitize your n95:
Cool and useful data: https://t.co/ftxQPW8ufR
— Anthony 😎🛹 (@djabatt) August 8, 2020
A lot of college football is cancelled. Pac 12 has postponed its season, the Big Ten has postponed, and other conferences are likely to follow:
Univ. of Nebraska joint statement: “We will continue to consult with medical experts and evaluate the situation as it emerges. We hope it may be possible for our student athletes to have the opportunity to compete."
— Bruce Feldman (@BruceFeldmanCFB) August 11, 2020
Big cities are taking huge hits. People are fleeing the cities as they are able to work from home, so home can be somewhere cheaper. Rents are dropping in metro areas. It might be hard for some cities to bounce back.
The Georgia school that made bad choices and punished its students for documenting them is now closed because of virus spread. Surprise, surprise. More on Georgia schools:
https://twitter.com/ai6yrham/status/1293216715791204352?s=20
It’s the end of a more rational era.
No, we’re probably not going to have a vaccine before election day. Not a safe one, anyway. Russia thinks skipping stage 3 trials is fine (it’s not):
#Russia claims it has reached the finish line for a #COVID19 vaccine — but has yet to hold Phase 3 human trials. "Stage 3 is everything," says @elizcohencnn. "You don't know if this vaccine works, and you don't know if it's going to kill people." pic.twitter.com/HohccFFHDF
— Quest Means Business (@questCNN) August 11, 2020
Vaping is not a great idea right now:
Teen vapers are 7 times more likely to get COVID-19, according to a new study by the Stanford University School of Medicine. https://t.co/BXMQG8x1es
— NBC News (@NBCNews) August 11, 2020
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